10 Best Cross-Chain Wallets With Ledger Support

In this article, I will discuss the Best Cross-Chain Wallets With Ledger Support. Selecting the best wallets is an important piece of the puzzle when it comes to the secure management of crypto assets spanning several blockchains.

With Ledger integration, these wallets enable you to keep your private keys offline while performing token swaps, staking, and accessing DeFi.

Here are the best wallets that encapsulate security, ease of use and, most importantly, cross-chain capabilities.

Key Points & Best Cross-Chain Wallets With Ledger Support

Wallet Name	Key Features
MyEtherWallet (MEW)	Ethereum-focused, NFT management, hardware wallet support
Zerion Wallet	DeFi portfolio tracking, swaps, NFT support, Ledger compatible
MetaMask	Web3 dApp access, token swaps, multi-network support, Ledger integration
Guarda Wallet	Multi-asset storage, staking, Web3 access, non-custodial
Trust Wallet	Supports 70+ blockchains, mobile-first, DApp browser, staking
SafePal Wallet	Supports 30,000+ assets, hardware + software wallet, multi-chain compatibility
ELLIPAL Titan 2.0	Air-gapped cold wallet, 10,000+ tokens, QR-based, Ledger compatible
Trezor Safe 5	Supports 8,000+ coins, EAL6+ secure element, multi-chain hardware wallet
Ledger Nano X	5,500+ coins, 100+ networks, Bluetooth, Ledger Live app
Keplr Wallet	Cosmos ecosystem, IBC protocol for cross-chain transfers, staking

10 Best Cross-Chain Wallets With Ledger Support

1. MyEtherWallet (MEW)

MyEtherWallet or MEW is an easy to use open-source Ethereum wallet that was created with the use of Ledger hardware wallets in mind.

Users are able to manage Ethereum and ERC-20 tokens through a USB Ledger hardware wallet.

MEW also offers token swaps, staking, and ENS domain management, and most importantly keeps your Ledger device’s private keys offline. This provides a great balance of security and control.

MyEtherWallet (MEW)

• Ledger Integration – Connects seamlessly with Ledger devices for secure key management.
• ERC-20 Token Support – Manage Ethereum-based tokens easily.
• Offline Security – Private keys remain offline on the Ledger device.
• Token Swaps & Staking – Supports token exchange and staking directly via MEW.
• ENS Management – Users can manage Ethereum Name Service (ENS) domains securely.

2. Zerion Wallet

Zerion Wallet is a decentralized finance (DeFi) portfolio tracker which includes support for Ledger hardware wallets.

Users can connect their Ledger device to Zerion’s interface to check and manage assets across Ethereum, Solana, and other chains.

This integration provides an overview of DeFi investments while keeping the private keys secured on the Ledger device.

Zerion Wallet

• Cross-Chain Support – Manage multiple blockchains including Ethereum and Solana.
• Ledger Compatibility – Integrates with Ledger hardware wallets for added security.
• DeFi Portfolio Tracking – Track all DeFi investments in one dashboard.
• Swap Functionality – Swap tokens across supported blockchains.
• User-Friendly Interface – Clean, intuitive UI for beginners and advanced users.

3. MetaMask

MetaMask is an Ethereum-based wallet that is compatible with Ledger hardware wallets for safe key management.

With access to a Ledger device, customers can administer their holdings on multiple EVM-compatible blockchains, including Ethereum, Binance Smart Chain, and Polygon.

Along with its ease of use and practically seamless access to decentralized applications, MetaMask has become an ideal option for users interested in DeFi and NFTs.

MetaMask

• Multi-Chain Access – Supports Ethereum, Polygon, Binance Smart Chain, and other EVM chains.
• Ledger Hardware Integration – Securely connects Ledger devices.
• dApp Browser – Access decentralized apps directly within the wallet.
• Token Management – Manage ERC-20 and ERC-721 tokens efficiently.
• Custom Network Support – Users can add and switch between multiple blockchain networks.

4. Guarda Wallet

Grarda offers another of its multi-currency wallets and this time lets clients link their wallets to Ledger hardware wallets for additional protection.

Ledger users can link their Ledger wallets to Guarda to manage over 50 chains and over 400,000 tokens!

With this integration, users can unlock a plethora of digital assets while their private keys remain safely housed storage on their Ledger device.

Guarda Wallet

• Multi-Currency Wallet – Covers 50 blockchains and more than 400,000 tokens.
• Ledger Integration – Securely connects to Ledger for offline key storage.
• Cross-Platform Access – Access on mobile, desktop, and web.
• Token Swaps – Swaps between cryptocurrencies supported within the wallet.
• Staking Options – Certain assets can be staked to earn rewards directly from the wallet.

5. Trust Wallet

Trust Wallet is a mobile cryptocurrency wallet that supports intrinsic Ledger hardware wallets for secure key management.

Users may link a Ledger device to Trust Wallet to observe and manage cross-chain cryptocurrency assets which include Ethereum and Binance Smart Chain.

This integration is the best of both worlds, in that Trust Wallet offers a seamlessly easy to use app, while Ledger offers the most secure protection.

 Trust Wallet

• Multi-Chain Support – Supports Ethereum, BSC, and multiple additional blockchains.
• Ledger Integration – Works with Ledger hardware wallets for secure storage.
• Mobile-Friendly – Available as an intuitive mobile app.
• dApp Access – Direct access to decentralized applications.
• Staking & Swaps – Within the app, supported tokens can easily be staked and swapped.

6. SafePal Wallet

SafePal Wallet allows you to manage a variety of digital assets with added security from Ledger hardware wallets. This combination lets a user link a Ledger to SafePal with multi-blockchain asset management available.

While you have access to all the digital assets you need, SafePal Wallet hardware wallets, SafePal’s Held, SafePal Wallet, and Ledger balances guarantee the security of all your digital assets.

SafePal Wallet

• Multi-Asset Support – Manage assets on different blockchains
• Ledger Support – Secure Ledger integration for offline key management.
• Token Swaps – Safe swapping of tokens within the app.
• Cross-Chain Capability Access multiple networks from one wallet.
• Security Focused – Private keys remain within the hardware device.

7. ELLIPAL Titan 2.0

The ELLIPAL Titan 2.0 is an air-gapped hardware wallet that supports Ledger hardware wallets for safe key management.

Instead of USB or Bluetooth connections, it utilizes QR codes for transactions, which vastly reduces potential attack vectors.

This integration protects users’ privacy while allowing them to securely manage their assets.

ELLIPAL Titan 2.0

• Air-Gapped Security – No USB or Bluetooth connections; uses QR codes for transactions.
• Ledger Integration – Works with Ledger for additional hardware security.
• Multi-Blockchain Support – Support Ethereum, Bitcoin, and many other networks.
• Cold Storage – Offline at all times.
• Mobile and Desktop – Companion secure apps for managing assets.

8. Trezor Safe 5

Trezor Safe 5 stands out as an industry-leading hardware wallet. With its seamless compatibility with Ledger hardware wallets, users can also securely manage keys and Ledger devices alongside the rest of their wallets on Trezor’s interface.

Trezor users can manage Ledger assets across multiple blockchains as well. The collaboration enables Trezor users to utilize the convenience of Trezor’s interface while also relying on the robust security tied to Ledger’s hardware wallets.

Trezor Safe 5

• Ledger Integration – Works with Ledger hardware wallets for secure asset management.
• Multi-Blockchain Support – Supports Ethereum, Bitcoin, and many more.
• Cold Storage Security – Offline on the device, private keys stored.
• User Friendly – Easy setup, and manage.
• Cross-Chain Token Management – Manage across blockchains.

9. Ledger Nano X

The Ledger Nano X is a hardware wallet that offers a broad selection of capabilities within a certain range of protective accessories for a wide range of cryptocurrencies.

Due to multiple wallet applications including Ledger Live, MetaMask, and others, wallet assets can be managed safely.

Being connected, having mobile features, and strong protective capabilities, the Ledger Nano X is a reliable option for the versatile user.

Ledger Nano X

• Bluetooth Enabled – Connect for on-the-go management.
• Wide Asset Support – Over 5,500 supported cryptos.
• Cross-Chain Access – Ledger Live, MetaMask and other wallets interlink.
• Secure Hardware Storage – Offline and encrypted, private keys.
• Mobile and Desktop Supported – Many apps work with Ledger Live.

10. Keplr Wallet

Keplr Wallet is a browser extension wallet for the Cosmos ecosystem. It supports Ledger hardware wallets for secure key management while users manages Ledger-enabled asset across Cosmos-based chains.

The integration access the Decentralized apps in the cosmos ecosystem while ensuring Private Keys are safe in the Ledger.

Keplr Wallet

• Cosmos Ecosystem – Best experience for the Cosmos and its connected chains.
• Ledger Integration – Link Ledger devices for safe management of your keys.
• Staking Support – Directly stake ATOM and other tokens from the Cosmos network.
• dApp Access – Use decentralized applications in the Cosmos ecosystem.
• Multi-Chain Portfolio – Seamlessly handle your assets on Cosmos-native blockchains.

Conclsuion

To conclude, the top Ledger-compatible cross-chain wallets combine safety, flexibility, and ease of use.

MetaMask, MyEtherWallet, and Ledger Nano X wallets keep private keys offline for security and permit the management of several blockchains simultaneously.

These wallets serve dependable and easy-to-use services for the handling of digital assets for decentralized finance (DeFi), staking, and token swaps.

FAQ